Trichomonas vaginitis causes

Etiology:
Trichomonas vaginitis is caused by Trichomonas vaginalis. When menstruation before and after the vaginal pH value changes, hidden in the glands and vaginal trichomoniasis in plica often to reproduce, cause inflammatory attack. Trichomonas vaginitis in patients with vaginal pH value of 5 ~ 6.5.

Pathogenesis:
Trichomonas vaginalis is a protozoan door - Animal flagellate Gang - Head Trichomonas - Trichomonas Branch - Trichomonas is only trophozoites without encapsulation period. Trophozoites for the pear-shaped or long oval 7 ~ 32μm wide 5 ~ 12μm, colorless and transparent, there is refraction, and 4 have a pre-flagellin and flagellin after. Fluctuations after the flagellar membrane along the back extension, but does not drifted away from the outside membrane fluctuations.

Because of the lack of an ideal animal model for the pathogenesis of trichomoniasis do not know much about. Trichomonas vaginalis trophozoites in the form of infection with the human, when a negative growth environment activities into non-spherical hard to identify with the host cells are often mistaken for cysts, but in high-power microscope can see fluctuations in membrane and flagellar activity microscopy should be attention to this point.

Trichomonal through its surface lectin (AP65AP51AP33AP23) and cysteine protease adhesion to vaginal epithelial cells, and amoeba-like through the exercise of mechanical damage as well as the secretion of proteolytic enzymes, protein dissolving enzyme cytotoxicity, direct contact and destruction of target cells, and induced by inflammatory mediators in the generation, the final cause epithelial cell lysis, loss, local inflammation happened. Trichomonas has the characteristics of Haemophilus and alkali-resistant, can consume, swallow vaginal epithelial cells within the host cell's glycogen utilization of glycogen and iron for energy metabolism, phagocytosis Lactobacillus, lactic acid generated hindered. The body can induce an immune response including cell-mediated immunity humoral immunity, complement activation reaction, to stimulate the host cells produce some cytokines cause local inflammatory changes.

Destruction of different strains of Trichomonas in vitro the ability of the different target nuclei, and different between the intrinsic toxicity of different strains.

Found clinically after the menstrual period often trichomoniasis increased use of oral