Simmonds disease

Simmonds disease, also known as anterior pituitary hypofunction, is lack secretion of pituitary hormones, lesions of pituitary or hypothalamus involve the endocrine function in pituitary gland. when the pituitary had destroyed, may produce the performance of endocrine gland hypofunction, the mainly involvement of the gland is sex gland, thyroid and adrenal cortex.

The disease was particularly prevalent in women that postpartum hemorrhage lead to ischemic necrosis of the pituitary. A variety of clinical manifestations, depending on the extent of pituitary damage, different causes, speed site, mostly is syndrome that due to a variety of pituitary hormone deficiency, but also is the lack of performance of a single hormone. Simmonds disease is caused by brain anterior pituitary dysfunction. Poor prognosis of Simmonds disease, any adverse stimulus such as the catch cold, infection, low blood sugar, salt, water, etc, can lead to serious or coma. When Simmonds disease is diagnosed, should early treatment.