Pituitary adenoma endocrine clinical manifestation

Pituitary as an important endocrine organ, contains a number of endocrine cells, secretion of a variety of endocrine hormones, if Pituitary Adenoma in some endocrine cell, may be occurred special clinical manifestation.

Endocrine clinical manifestation in different types of pituitary adenoma as follow:

1. growth hormone cell adenoma: Early tumor size of only a few millimeters, the main clinical manifestations of excessive secretion of growth hormone. Patients with minor growth can occur too fast, or even develop into a giant. Adults since the performance of acromegaly. From a sense of severe generalized weakness, headache and joint pain, sexual dysfunction, amenorrhea, infertility, even complicated by diabetes.

2. prolactin cell adenoma: clinical manifestations of amenorrhea, galactorrhea, infertility, weight loss, pale and delicate skin, subcutaneous fat increased, as well as weakness, easy fatigue, lethargy, headaches, sexual dysfunction and so on. Performance for men loss of libido, impotence, breast hyperplasia, sparse beard, who re-genital atrophy, reduced sperm count, infertility, men with no more than women change.

3. adrenocorticotropic hormone cell adenoma: clinical manifestations of concentric body fat, full moon face, buffalo back, sanguine temperament, large abdomen legs purple skin pattern, such as an increase in vellus hair. Amenorrhea in serious cases, loss of libido, generalized weakness, or even bedridden. Some patients also have high blood pressure, diabetes and so on.

4. thyroid-stimulating hormone cell tumor: a rare, due to secretion of pituitary thyroid stimulating hormone excessive, causing symptoms of hyperthyroidism, after removal of pituitary tumor in hyperthyroidism symptoms disappear. Otherwise the feedback caused by low thyroid function occurred in focal pituitary gland hyperplasia, gradually developed into a pituitary adenoma, grow up can also be caused by sellar expansion of the oppressed around the symptoms of the Organization.

5. follicle-stimulating hormone cell adenoma: a very rare clinical manifestation of sexual dysfunction, amenorrhea, infertility, reduced sperm number.

6. melanin-stimulating hormone cell adenoma: a very rare clinical manifestation of the black skin calm, not accompanied by increased cortisol.

7. endocrine inactive adenomas: the special feeling of the early patients had no tumor grew up to oppression of pituitary insufficiency pituitary of clinical manifestations.

8. malignant pituitary tumor: a short history, the disease progress rapidly, not only pituitary tumors grow oppression and violations of the four-week, bone destruction caused by saddle or immersion at the end of the cavernous sinus, oculomotor nerve paralysis caused by nerve or outreach. Sometimes, tumor perforation saddle up to the end of the sphenoid sinus, the short-term neurological symptoms not obvious.