Parosteal osteosarcoma

What is Parosteal osteosarcoma?
Parosteal osteosarcom is Originated in the periosteum around the bone to bone growth, but tends to enveloping the core, more rare, the incidence rate was similar for men and women, although can be found in any age, but more than half of more than 30 years of age.

What are causes of Parosteal osteosarcoma?
Cause of Parosteal osteosarcoma is not yet fully unknown, may be epiphyseal cartilage growth free from the surface to the bone can also be the origin of cells in the tympanic membrane or the origin of the tendon attached to the pre-cartilage fibrous tissue, genetics, body abnormal chromosome 8,11,19 and Osteochondroma of the occurrence of a certain relationship

What are Symptoms of Parosteal osteosarcoma?
Minor symptoms can be pain-free, only for the mass performance, sometimes a great mass, such as the femur is located at the bottom of the rear, can affect the normal range of motion. Similar benign natural course of disease, 75% of slow growth, after repeated resection of recurrent, can survive for more than 5 years, 25% for invasive, similar to the biological behavior of sarcoma sclerosis. Seen mainly in the metaphysis of long bones, especially the distal femur, proximal tibia and proximal humerus or see X-ray the new bone formation in many nests, slow growth, synthesis of tumor tends to collect pieces of material, the edge often lobulated, round , a small tumor of the bone trabecula, bone and mother of early boundaries clearly shows a narrow translucent zone article. Continue to the limits of biological disappear. Deep dense, uniform. Invasion of poor, the cortical and cancellous bone are not involved; attack obviously, the cortical damage, erosion marrow, resulting in osteolytic areas, with new bone formation between the kitchen, CT in determining whether or not the violation of valuable marrow. Transfer of late, but there are also a little full of early transfer of the occurrence of invasive.

How is diagnosis for Parosteal osteosarcoma?
Parosteal osteosarcoma is diagnosed by X-ray. X-ray can see a number of new bone formation of the nest, the slow growth of tumor tends to collect pieces of synthetic material, the edge often lobulated, round, a small tumor of the bone trabecula, bone and mother of early boundaries clearly shows a narrow section translucent zone. Continue to the limits of biological disappear. Deep dense, uniform. Invasion of poor, the cortical and cancellous bone are not involved; attack obviously, the cortical damage, erosion marrow, resulting in osteolytic areas, with new bone formation between the kitchen, CT in determining whether or not the violation of valuable marrow. Transfer of late, but there are also a little full of early transfer of the occurrence of invasive.

How is treatment for Parosteal osteosarcoma?
Parosteal osteosarcoma is treated depends on the location, size, and invasive, according to the Huvos grading and Farn, Ⅰ - Ⅱ large class can be removed, of course, need to have a normal soft tissue and bone beneath the gap, Ⅲ - Ⅳ is the first choice of amputation level with high-dose a variety of chemotherapy, the drugs chosen for the breeding cycle of the main tumor.