Diagnosis of osteogenesis imperfecta mainly is X-ray examination and laboratory tests:
1, X-ray examination: X-ray is mainly expressed in Osteopenia and osteoporosis.
performance in the long bones slender, sparsely trabecular bone, were like semi-transparent, such as pencil thin cortex draw. Medullary cavity is relatively large, can be serious when there is cystic change. Expansion of bone at both ends was pestle-shaped, we can see there is a number of old or fresh fractures. Some of them have abnormal connections, the backbone of bending. There is some deformity is caused by muscle traction adherent area, such as coxa vara, femoral and tibial bow was. Some patients will be formed in the fracture-rich globular callus, the number and scope, it will be misdiagnosed as osteosarcoma. Some patients with cortical thickness, hereinafter referred to as "thick bone."
delay skull calcification, bone thinning, double the temporal bone uplift, the former chimney large, relatively dense petrous bone, skull base flat. Primary calcification poor development of permanent teeth.
vertebral thinning, double-concave, sparsely trabecular, double convex disc compensatory enlargement. Scoliosis can have deformities or after the process.
ribs from the rib corner bend down, often see multiple fractures. Triangular pelvic, pelvic smaller.
2, laboratory tests: Generally normal, sometimes there is blood alkaline phosphatase increase, this may be due to traumatic fracture, the activity of osteoblasts increased. Very severe cases, there is plasma calcium and phosphorus reduction, but rarely see.
