Neonatal respiratory distress syndrome Treatment

1. general treatment (Nursing):

1) insulation: placed infant in the warm box-controlled hub-and-rescue platform or to maintain skin temperature at 36.5 ℃.

2) monitoring: temperature, respiration, heart rate, blood pressure and blood gas.

3) to ensure the supply of fluids and nutrition: the 1st day of 5% or 10% glucose solution 65-75ml / (kg.d) gradually increased to 120-150ml / (kg.d) and added electrolyte condition changed after a turn for the better oral feeding, lack of energy so that part of parenteral nutrition supplemented.

4. close patent ductus arteriosus: should be strictly limited to the amount of fluid and give diuretics, such as the still closed, will be intravenous indomethacin, the dose for each of 0.2mg/kg, the first hour after administration to do all by 12,36 1, a total of 3 times. The mechanism as follows: prostaglandin E is the fetal and early postnatal patent ductus arteriosus open to maintain an important material, and the prostaglandin synthetase inhibitor (indomethacin) can reduce prostaglandin E synthesis. Catheter closure of help. Used to five could be considered null and void ligation.

5. antibiotics: According to secondary infection in the lungs of the pathogen (bacterial culture and sensitivity) the application of appropriate antibiotic treatment.

2. oxygen therapy and mechanical ventilation:

1) oxygen: In accordance with the degree of selection of cyanosis nasal catheter, mask or hood oxygen, in preterm infants prone to occur due to oxygen toxicity, so in order to maintain PaO250-70mmHg (6.7-9.3kPa) and appropriate TcSO285% -92%.

2) continuous positive airway pressure and normal frequency mechanical ventilation.

3) Others: high frequency oscillation or high frequency jet ventilator, can often reduce the frequency of the negative effects ventilator in order to obtain better results.

3. PS Alternative medicine:

PS can reduce respiratory distress syndrome mortality and the incidence of pneumothorax,at the same time improve the pulmonary ventilation function, reduce ventilator parameters, PS has been conventional for the prevention or treatment of RDS.

1) PS: including natural, semi-synthetic and synthetic three.

2) Usage: Once the diagnosis, PS should be used as soon as possible (within 24 hours after birth) by endotracheal intubation in supine position respectively, the right of supine, left side lying and supine position and then the 1 / 4 the volume of airway slowly into each Application of recovery after injection of pressurized capsule 1-2 minute ventilation, PS different preparations, the dose and administration interval of time varies, depending on the condition to be 2-4 times.