Myocarditis Diagnosis

Myocarditis is diagnosed by clinical manifestation, symptoms and some tests. If found that significantly impaired heart such as arrhythmias or heart failure, and ECG shows the myocardial changes such as ST-T changes and ectopic rhythm or conduction disturbances, the myocarditis can be confirmed diagnosis.

If the doctor suspect patient with viral myocarditis, will examine probability of HIV infection. Evidence of HIV infection have the following expression:

1. fever, diarrhea or flu symptoms, occurred shortly after the emergence of symptoms or ECG changes of heart.

2. serum determination of virus neutralizing antibody-positive results, due to Coxsackie B virus, the most common, is usually detected in this group of viruses and antibodies, in the early onset and 2 to 4 weeks a pleasing specimen of blood, such as the secondary antibody 4 times the price that one up or ≥ 1:640, recent infection can be used as the basis for the virus.

3. pharynx, anal swabs of virus isolation, such as auxiliary positive significance, and some normal people can also be positive, its significance with positive results and a combination of antibodies.

4. Polymerase chain reaction detected virus RNA from stool, serum or myocardium.

5. Myocardial biopsy: HIV testing from obtained living tissue, virology examination can help to diagnosis of myocarditis.

Some tests use to myocarditis diagnosis include:

1. Blood test: white blood cell count in viral myocarditis may be normal, high or lower, most of the normal erythrocyte sedimentation rate can be slightly faster, C-reactive protein are mostly normal, GOT, GPT, LDH, CPK normal or increased number of chronic myocarditis in the normal range.

2. Electrocardiogram: ECG abnormal high positive rate and an important basis for the diagnosis, after the onset of ECG from the normal can become abnormal suddenly, with the infection subsided and disappeared. The main performance of ST segment depression, T wave of low-or inversion.

  • ST-T changes: T wave inversion or reduce common, sometimes showed ischemic changes in T wave; ST shift could be mild.
  • Arrhythmias: In addition to sinus tachycardia and sinus bradycardia, the ectopic pacemaker and the common block. Atrial, ventricular, atrioventricular junction premature beats may occur, independent of atrial or junctional tachycardia, paroxysmal sustained or sustained ventricular tachycardia, atrial flutter or ventricular, fibrillation.

    3. X-ray examination: no abnormal changes in focal myocarditis. Diffuse myocarditis or pericarditis in patients with combined heart shadow expansion of cardiac decline can be seen severe cases of congestive lung or pulmonary edema.

    4. Echocardiography: can left ventricular systolic or diastolic dysfunction, segmental and regional wall motion abnormalities, ventricular wall thickness increased myocardial echo reflectivity enhancement and uneven, the expansion of the right ventricle and abnormal movement.

    5. Radionuclide examination.

    6. Virology examination: from the throat swab or stool, or myocardial tissue isolated viruses, detection of serum specific anti-HIV antibody titration, the myocardial biopsy specimens from the immunofluorescence method used to find specific antigen, or found in the electron microscope virus-like particles, as well as polymerase chain reaction from the feces, serum, virus was detected in myocardial tissue RNA.