Home › Bone, joint & Muscle Disorders

Multiple Myeloma Treatment

1. General treatment for Multiple Myeloma with Complications:

  • hemoglobin less than 60g / L, red blood cell transfusion;
  • hypercalcemia: isotonic saline hydration, prednisone: 20mg, oral, 3 ~ 4 times / day;
  • Hyperuricemia: Allopurinol: 0.2mg, oral, 3 times / day;
  • Hyperviscosity Syndrome: plasma exchange treatment;
  • renal failure: hemodialysis;
  • infections: combination antibiotic therapy for patients with repeated infection penicillin, gamma globulin effective preventive injection.

    2. Chemotherapy: medication: Melphalan 2mg, oral, 3 times / d; prednisone 20mg, oral, 3 times / d, treatment 7d, 6 weeks to repeat treatment 1 to 2 years. M2 program: BCNU 25mg / m2, cyclophosphamide 400 mg/m2, vincristine 1.4 mg/m2, both intravenously day 1; Ibid melphalan, prednisone 40 mg/m2, oral, 14 days. refractory MM chemotherapy: VAD program: vincristine 0.5mg / d, doxorubicin 10mg / d, dexamethasone 40mg / d, are the first 1 ~ 4,17 ~ 20 days by intravenous drip. VBAP program: vincristine 2mg / d, nitrogen cards mustard 60 ~ 80mg / d, adriamycin 40 ~ 60mg / d, are the first intravenous injection of 1 day, prednisone 60 ~ 100mg / d, take orally in the first 1 - 5 days.

    3. Radiotherapy: for the limitations of myeloma, localized bone pain and spinal cord compression have symptoms.

    4. A-interferon: 3 to 5 million u / day, subcutaneously, 3 times / week, treatment> 6 month.

    5. Bone marrow transplantation: autologous bone marrow, autologous peripheral blood stem cell and allogeneic bone marrow transplantation can be used for the treatment of multiple myeloma.

    • Submitted by Health Studies on Wed, 04/08/2009 - 23:30
    Category: