Multiple Myeloma Causes

Multiple myeloma is caused by ionizing radiation, chronic antigen stimulation, genetic factors, viral infection, gene mutation. Ionizing radiation can induce the disease, its incubation period is longer, sometimes up to more than 15 years, according to the report of chemical substances such as asbestos, arsenic pesticides, petroleum chemical products and rubber plastic type of long-term exposure may trigger the disease. Clinical observation that patients with chronic cholecystitis osteomyelitis, pyoderma, such as chronic inflammation of patients prone to MM. Chronic inflammation can be induced to stimulate intra-abdominal plasmacytoma in certain ethnic MM (such as black) is higher than the incidence of other ethnic groups. Living in the same area the incidence of different races have different, which prompted the cause of multiple myeloma may be related to genetic factors.

Myeloma patients in cultured dendritic cells were found with the Kaposi's sarcoma-associated herpes virus, which prompted the contact between the two must exist. Human IL-6 can promote tumor growth in bone marrow, at the same time to stimulate the reabsorption of bone.