Multiple myeloma, also called myeloid tumor, is a malignant tumor that plasma cell abnormal growths. Multiple myeloma is a progressive disease of the tumor. It is characterized by bone marrow plasma cell tumors and the integrity of a monoclonal immunoglobulin (IgG, IgA, IgD or IgE) or Bence Jones protein (free of single - clonal light chain κ or γ) hyperplasia, extensive infiltration and a large amount of monoclonal immunoglobulin deposition appearance and normal polyclonal plasma cell proliferation and polyclonal immunoglobulin secretion was inhibited. multiple myeloma there is often accompanied by multiple osteolytic lesions, hypercalcemia, anemia, kidney damage, but also the susceptibility of bacterial infections increase the generation of normal immune globulin inhibited. incidence rate is estimated to be 2 ~ 3 / 100000, male to female ratio of 1.6: 1, most patients with age> 40 years of age. black is white patients with 2-fold.