Mitral regurgitation Causes

Rheumatic fever is the main causes of mitral valve damage, it account for 1/3 the mitral regurgitation causes, and was particularly prevalent in the male. Mitral regurgitation was mainly due to inflammation and fibrosis that cause bicuspid valves to shorten and hardened, deformation, adhesion integration. About 50% of patients with mitral stenosis. Other Mitral regurgitation causes include:

1. coronary atherosclerotic heart disease (CHD): myocardial infarction and chronic myocardial ischemia after the affected papillary muscle and adjacent ventricular myocardium, caused by papillary muscle dysfunction with fibrosis.

2. congenital malformations: cleft mitral valve, the most commonly found in endocardial cushion defect or correct cardiac translocation; endocardial fibroelastosis; parachute-type mitral valve deformity.

3. mitral annular calcification: idiopathic degenerative disease, more common in elderly female patients. In addition, hypertension, Marfan syndrome, chronic renal failure and secondary hyperparathyroidism in patients with thyroid function, but also prone to mitral annulus calcification.

4. left ventricular expansion: any cause of the apparent expansion of left ventricle, can both lead to mitral annulus expansion, and papillary muscle displacement, the impact valve leaflets to close, finally cause mitral insufficiency.

5. mitral valve prolapse syndrome.

6. other rare causes: connective tissue diseases such as systemic lupus erythematosus, rheumatoid arthritis, etc.; hypertrophic obstructive cardiomyopathy; ankylosis spondylitis sclerosis.

More acute mitral regurgitation due to chordal rupture, valve damage or rupture, papillary muscle necrosis, or fracture, as well as cracking after artificial valve replacement, can be found in infective endocarditis, acute myocardial infarction, or penetrating Blunt chest injuries spontaneous rupture tendons.