Malignant and Invasive Hydatidiform mole Diagnosis

Diagnosis for Malignant Hydatidiform mole:
According to history and clinical manifestations, combined with tests for diagnosis of Malignant Hydatidiform mole:

1. Urine pregnancy test: after emptying of hydatidiform mole over two months later, also confirmed by curettage without residual blister-like moles, and urine pregnancy test remained positive, or negative and then positive to have malignant potential.

2. X-ray: malignant mole always lung metastasis can occur, so cough, hemoptysis, and the need for lung examination, we can see the shadow of cotton cloth Bulk everywhere in the lungs, especially seen in the right lung lower lobe. Without lung disease, and erosion can not rule out the mole.

3. Diagnostic curettage: If only vaginal bleeding, other symptoms and signs are not typical, they can make a diagnostic curettage, if a small amount of decidual driven or necrotic tissue, invasive mole can not be ruled out.

Diagnosis for Invasive Hydatidiform mole:
1. History and clinical manifestation: Based on mole removal within six months after the clinical manifestation of typical symptoms or metastases, combined with tests to confirm diagnosis for Invasive Hydatidiform mole.

2. HCG Determination: mole removal for more than eight weeks after the β-HCG remained high, or HCG dropped to normal levels once again increased rapidly, clinical residual mole has been ruled out, luteinized cyst or pregnancy can be diagnosed as the erosion of mole.

3. B-Ultrasound: B-mode ultrasound for non-invasive examination, early detection can be invasive mole myometrial the degree of organization to help with diagnosis of uterine trophoblastic tumor lesions. Palace wall shows focal or diffuse light, or light and dark areas and white Mission cellular-like lesions, consideration should be given for invasive mole or choriocarcinoma.

4. Histological diagnosis: curettage specimens alone can not be used as invasive mole based on the diagnosis, but invasive uterine myometrium or outside the slice, that the structure or villous villus degeneration signs can be diagnosed with invasive mole . If the primary tumor and metastasis inconsistent diagnosis, as long as any of the structure of specimens in the villi, which should be diagnosed as invasive mole.

Malignant and Invasive Hydatidiform mole diagnosis basis:
1. Within six months after curettage of hydatidiform mole, arise irregular vaginal bleeding, hemoptysis, cough, headache, vomiting, paralysis, etc..

2. Vaginal wall can be seen the transfer of violet blue nodules.

3. Uterus increased, side uterus mass, ovarian cyst luteinized.

4. Hematuria hcG level from low to high, or once again to the positive-negative.

5. Chest X-ray can see the shadow of a number of cotton-like mission.

6. Tomography or CT found skull lesions.

7. Shows trophoblastic cells active hyperplasia, a large number of hemorrhagic necrosis in organization, can see the structure of villi.