Kawasaki disease Symptoms
Main symptoms of Kawasaki disease include: common persistent fever, 5 ~ 11 days or longer (2 weeks to 1 month), the body temperature is 39 ℃ or more often, antibiotic treatment is invalid. Common symptoms is bilateral conjunctival congestion, flushing lips, there are chapped or bleeding. Edema was rigid hands, the palm and foot flushing early. After 10 days, occur peeling sheet in finger and toe. Symptoms also have acute non-suppurative cervical lymph node swelling, the most significant of neck, more than 1.5cm in diameter, most occur in the side, a little tenderness, often occur after fever 3 days and heal after a few days. Soon after Fever (about 1 ~ 4 day), occur erythema or skin rash, often on the trunk, but not herpes and crusted, dissipated within a week.
Other Kawasaki disease symptoms include: often occur heart damage, myocarditis, pericarditis and endocarditis. Patients have accelerated pulse, tachycardia could be heard at auscultation, gallop rhythm, heart sounds low blunt. Systolic murmur more often. Mitral valve can occur, and heart failure. For echocardiography and coronary angiography, can be found, see the majority of patients have coronary artery aneurysms, pericardial effusion, left ventricular enlargement and mitral regurgitation. X-ray film shows that the expansion of the heart. Occasional joint pain or swelling, cough, runny nose, abdominal pain, mild jaundice, or aseptic meningitis performance. Acute phase of about 20% of cases occur perineal, perianal skin flushing and desquamative and 1 ~ 3 years ago, the original site of BCG vaccination or scar erythema reproduction. Transverse nail groove recovery can be seen spinning.
The first phase of Kawasaki disease is acute febrile period, the general course of 1 ~ 11 days after symptoms start to appear in the fever can be severe myocarditis. The second period is sub-acute period, generally 11 to 21 days duration, the majority of the body temperature drop, eased symptoms, have membranous peeling at finger and toe. Severe cases of fever is still sustainable. Occurrence of coronary artery aneurysms can lead to myocardial infarction, aneurysm rupture. The majority of patients in the first four weeks into the third period of that recovery period, generally 21 to 60 days duration, clinical symptoms subsided, such as no significant coronary artery disease that is gradually resuming; have coronary artery aneurysms is still sustainable development, can occur myocardial infarction or ischemic heart disease. A small number of patients with severe coronary artery aneurysm into the chronic phase can be prolonged for several years, the legacy of coronary artery stenosis, the occurrence of angina, heart failure, ischemic heart disease, myocardial infarction can be life-threatening.