Hyponatremia Symptoms

When the blood Na + more than 125mmol / L, hyponatremia have no symptom. [Na +] at 125 ~ 130mmol / L between, there are only symptoms of the gastrointestinal tract. The main symptoms is weakness, fatigue, nausea and vomiting, headache and sleepiness, muscle cramps and reversible neuropsychiatric, ataxia, etc... At the early hyponatremia, brain cells inside and outside of the cells have adaptive regulation of osmotic pressure imbalance. At 1 ~ 3h, the brain extracellular fluid into the cerebrospinal fluid and then return to systemic circulation; such as the persistence of hyponatremia, brain cells are the cells to adapt to regulation of organic solute permeability, including phosphoric acid, creatine, inositol and amino acids (such as alanine, taurine) in order to reduce cell edema lost. If the brain cells to adapt to regulation of such failure, edema of brain cells are to be followed by. Clinical manifestations have convulsions, stupor, coma, and symptoms of intracranial hypertension. If hyponatremia occurred within 48 hours, then there is great danger, can lead to permanent damage to the nervous system consequences. Chronic hyponatremia, and then there is the risk of demyelinating permeability happen, especially in correcting hyponatremia too much or too easy to happen when. In addition to brain cell edema and intracranial hypertension clinical performance, because of reduced blood volume, blood pressure may be low, small veins and circulatory failure rate, the signs at the same time there is water loss.