1. The lack of parathyroid hormone (PTH) or the role disruption:
Primary or idiopathic hypoparathyroidism uncommon, belong to autoimmune diseases, and thymic development does not exist at the same time said DiGeorge syndrome, such as simultaneously with thyroid dysfunction and adrenal cortex are called multiple endocrine hypofunction disease. In clinical secondary hypoparathyroidism see patients more commonly found in patients with hyperthyroidism radioactive iodine treatment or thyroid surgery removed due to injury.
2. The lack of vitamin D or metabolic abnormalities:
A lack of vitamin D: in the absence of food, intestinal absorption, exposure to sunlight is too small, repeated pregnancy, such as long-term breast-feeding.
Obstacles to the hydroxylation of vitamin D: found in liver cirrhosis, renal failure, hereditary L-a-hydroxylase deficiency and other diseases, the latter for the vitamin D-dependent rickets I type.
Vitamin D resistance: end-target organ of 1,25 (OH) 2D3 is not sensitive to vitamin D-dependent rickets type II.
3. Chronic renal insufficiency.
4. Acute pancreatitis.