Hydatidiform mole Diagnosis

Hydatidiform mole Diagnosis is based on Clinical manifestations. If three months of amenorrhea later, occur vaginal bleeding, much or little blood, was intermittent, in most cases the uterus is greater than the month of menopause are also possible. Uterine size of up to four to five months of pregnancy when fetal movement is not only pregnant women do not feel, touch less than moles, have not heard of fetal heart rate. Double-check vaginal bleeding, if found blister-like fetus blocks, can confirm diagnosis for Hydatidiform mole.

Abdominal B ultrasonic scan: can shows that there may be the size of the uterus, ranging from the dark zone, is due to intrauterine hemorrhage. Also found that child, that is, except for snow-rays, but also may have the fetus and / or placenta image. Diagnosis of B-instrument without any trauma, confirmed a high rate, for the diagnosis of hydatidiform mole is an effective measure.

HCG Determination: hCG quantitative test of the accuracy of diagnosis and follow-up for an important test of hydatidiform mole. hCG in normal pregnancy less than the beginning, and in 8 to 10 weeks pregnant and reached the peak hours, and then gradually decreased. Gestational age (100 days) after, hCG decreased significantly. In the dual (and more) when the pregnancy, hCG was also higher than single births. Amount of hCG in the mole higher than normal, and continued for a high level. Non-pregnant women in the normal amount of hCG in serum <75mIU/ml, β-hCG <20mIU/ml. Serum of normal pregnant women in the median peak value of 100,000 mIU / ml below the maximum value of 210,000 mIU / ml, and serum of patients with hydatidiform mole hCG value is much higher than 200,000 mIU / ml. Therefore, to the combined clinical and B-, high-value individual hCG, to determine the diagnosis of hydatidiform mole. As do the quantitative stage of follow-up inspection hCG, after 14 weeks in pregnancy hCG value is still high-value, then the diagnosis could have been more clear.

Grape excluded for more than eight weeks, after careful curettage confirmed no residual intrauterine mole, the existence of non-luteinized cysts, serum hCG remains at or above 1000mIU/ml also increased after malignant transformation hyperchromic confirmed. hCG values below and 1000mIU/ml luteinized cyst exists, still need to be careful to check for the existence of the transfer of disease or may be due to ovarian cysts caused by luteinized should closely follow-up. Dissipated, such as luteinized cysts, with the decline in hCG, according to follow-up of benign mole.

Immunization (sheep red blood cell agglutination inhibition test, etc.) analysis: normal test morning urine hCG with pregnancy, the highest concentrations generally in the 160,000 IU / L following, occasionally up to 640,000 IU / L. Diagnosis of hydatidiform mole in the 500,000 ordinary ~ 600,000 IU / L between, and the continued decline.