Hydatidiform mole Causes

Hydatidiform mole Causes is unknown. A study found that the incidence of hydatidiform mole is related with nutritional and age. The etiology, age is a significant factors of Hydatidiform mole, age greater than 40 years of age the incidence of hydatidiform mole than 10 times of young women, age is the high-risk complete hydatidiform mole factors, the two age groups of women are prone fertilization defects.

Through the combination of pathology cytogenetic study shows genetic characteristics of different Hydatidiform mol. Complete Hydatidiform mole is the source of the male genome, that is, the egg in the loss of eggs or egg prokaryotic prokaryotic inactivation spermatogonial circumstances and development of the formation of nuclear combination. Diploid karyotype, 90% were 46, XX, from an empty egg (egg-free genetic material) with a haploid sperm (23, X) fertilized by a diploid self-replication to resume (46, XX), further growth and development by, known as the empty egg fertilization. Its a small number of nuclear-type for the 46, XY, these are two different sperm sex chromosome (23, X and 23, Y) empty eggs fertilized at the same time it is called double fertilization sperm. Partial hydatidiform mole is often triploid karyotype, 80% for the 69, XXY, The rest are 69, XXX or 69, XYY, from a normal egg and sperm double fertilization, resulting in a set of extra chromosome composition of the father ; also available as a result of a normal haploid egg (or sperm) and diploid gametes meiosis failure due to combination.