Hydatidiform mole

Hydatidiform mole is disappearance of villi at microvascular matrix, villous stromal fluid in order to form a bubble size, the shape of grapes. Organizational characteristics of Hydatidiform mole: trophoblastic cell hyperplasia; villous edema; Stromal vascular villi disappear.

Hydatidiform mole divided into complete and partial hydatidiform mole, the majority of complete hydatidiform mole. Clinical diagnosis of hydatidiform mole are entirely in terms of means; some mole with placenta and / or the fetus, and is known as partial hydatidiform mole. Spontaneous abortion in the organization found 40 percent of patients have some degeneration of the blisters, but not diagnosed as hydatidiform mole.

Complete hydatidiform mole: placental villi of all involved, no baby and its adjunct, cavity filled blisters; partial hydatidiform mole: Only part of placental villi vesicular degeneration occurs, there are survival or intrauterine dead embryos.

Malignant hydatidiform mole is condition that Vesicular mole tissue expands to the uterine cavity, and deep myometrial invasion or metastasis occurred in other parts of the body. The chance for 5% ~ 20% of hydatidiform mole or malignant evil into choriocarcinoma, hydatidiform mole removed most of them in six months, but also discharged before the mole is not malignant transformation occurred in persons. Although malignant tumors with malignant characteristics of hydatidiform mole, but the treatment effect and prognosis is better than those of choriocarcinoma.

Invasive Hydatidiform mole is condition that Vesicular mole tissue local myometrial invasion, a small number of transferred to the uterus. Erosion from the benign hydatidiform mole, mole removal in the majority within 6 months after the occurrence. Invasive hydatidiform mole villi can myometrial or vascular invasion or both, at first for the local spread of blister-like tissue deep myometrial invasion, and sometimes completely penetrate the uterine wall and expand into the broad ligament or the abdominal cavity, half of cases Go the distance with the blood running, the main parts of the lung and vagina. Better prognosis. Blisters invasive myometrial tissue or transferred to the neighboring and distant palace browser invasive mole said. Mole removal and more in 6 months after the occurrence of myometrial perforation or can be transferred to the lungs, vagina, vulva and other organs, resulting in partial destruction of bleeding. Invasive mole with malignant characteristics, but the treatment effect and prognosis is better than choriocarcinoma, treatment is chemotherapy or surgery.