Hemorrhagic disease Treatment

Etiological treatment:

Acquired hemorrhagic disease, the target must be the cause for active treatment in order to achieve the purpose of treatment. Drug-induced thrombocytopenia more common, requiring adequate attention to rational drug use; liver disease caused by the need to improve liver function. Of hereditary hemorrhagic disease type 1, is still a lack of radical measures have not been widely used in gene therapy should emphasize the prevention of trauma, surgery is necessary, the need to make up for the lack of clotting factor, to ensure that surgery and postoperative bleeding did not happen until the wound healing so far. There is genetic engineering has been the synthesis of coagulation factors can be used, and go after virus treatment, safer clinical application.

Hemostasis Treatment:

1. Local hemostasis for the bleeding to stop children, first of all, local hemostasis taken:
(1) oppression or pressure dressings.
(2) ice pack.
(3) add cotton balls drip adrenergic partial oppression.
(4), thrombin, fibrinogen, fibrin sponge enzyme thromboplastin, starch sponges, oxidized cellulose fiber protein, such as absorbable gelatin sponge.

2. Hemorrhage caused by vascular factors in treatment. Commonly used: rutin; Kabak network (network of blood-an); etamsylate (bleeding-min); vitamin C.

3. Platelet factors in the treatment of bleeding. Available: prednisone; blood transfusion; platelet concentrate transfusion.

4. Haemorrhage caused by a lack of clotting factor treatment. Available: transfusion; added the missing clotting factor; plasma transfusion; vitamin K related to the lack of clotting factor, to give vitamin K (natural vitamin K for K1, K3 for synthetic agents, with less side effects); the lack of red blood cells of children with G6PD enzyme, vitamin K agents can cause hemolytic anemia.

5. Fibrinolysis due to the treatment of bleeding. Available: amino acid has been (EACA); PAMBA (anti-fibrinolytic acid); tranexamic acid (acid hemostasis, coagulation acid, t-AMCHA); aprotinin. This enzyme has the role of anti-fibrinolytic, and anticoagulant effect, it should be analysis of the use of the sick child's specific condition and the suitability of blood coagulation status before making a decision.