Hemolytic uremic syndrome

Treatment of HUS is supportive, include management of fluids and electrolytes, blood transfusion, plasma exchange (plasma remove and replace), kidney dialysis.

HUS is diagnosed by CBC, blood clotting tests, urinalysis, stool cultures; Abnormalities include anemia, thrombocytopenia, uremia, blood and protein in urine and E. coli O157:O7.

Complications of HUS are renal failure, hypertension, hematuria, TTP, neurologic dysfunction, gastrointestinal, pancreatitis, cardiac dysfunction and more.

Symptoms of HUS are abdominal cramping, vomiting, profuse bloody, watery diarrhea, weakness, fatigue, low or no urine output, unexplained bruises or bleeding, paleness, yellow skin.

HUS often is caused by an infection with E. coli O157:H7 or other bacteria, and viral infection such pneumonia bacteria, autoimmune disease such AIDS, blood infection, medications such mitomycin C, pregnancy and postpartum.

E coli O157:H7 is a strain of the bacterium Escherichia coli, It causes foodborne illness, colitis and bloody diarrhea by producing a toxin called Shiga toxin, which damages the intestines.

Hemolytic uremic syndrome, HUS, is a condition characterized by the destruction of red blood cells and kidney failure that is associated with microangiopathic hemolytic anemia and thrombocytopenia.