Hemolytic uremic syndrome: Complications

What are the Complications of Hemolytic uremic syndrome?

  • Chronic renal failure.
  • Acute renal failure usually lasting about 2 weeks and requiring hemodialysis occurs.
  • Hypertension.
  • Hematuria.
  • Thrombotic thrombocytopenic purpura.
  • Neurologic dysfunction ,Seizures, coma, stroke, hemiparesis, and cortical blindness. Severe CNS involvement is associated with significant mortality.
  • Gastrointestinal involvement, including any area from the esophagus to the anus. This can include hemorrhagic colitis, bowel necrosis and perforation, and intussusception, intestinal strictures, severe colitis.
  • Cardiac dysfunction, possibly precipitated by uremia and fluid overload.
  • Pancreatitis. Although seen in fewer than 10% of patients, can include glucose intolerance and may lead to diabetes.
  • Cerebral involvement.
  • Hepatomegaly