Glucose-6-phosphate dehydrogenase deficiency Symptoms

Glucose-6-phosphate dehydrogenase deficiency do not display any signs and symptoms until their red blood cells are exposed to certain chemicals in food, medicine, infection, or to stress. In more serious cases, the most significant consequence of G6PD deficiency is hemolytic anemia. The major symptoms of hemolytic anemia are jaundice, dark urine, abdominal pain, back pain, lowered red blood cell count, and elevated bilirubin.

Symptoms of G6PD deficiency are more common include:

• Neonatal jaundice
• Favism
• Asymptomatic
• Shock
• Fever
• Chills
• Abdominal pain
• Back pain
• Hemoglobin in the urine
• Kidney failure
• Paleness
• Yellow eyes
• Darkened urine
• Fatigue
• Shortness of breath
• Rapid heart rate

Newborns with G6PD deficiency are about 1.5 times as likely to get neonatal jaundice than newborns without G6PD deficiency. Once the trigger is removed or resolved, the symptoms of G6PD deficiency usually disappear fairly quickly, typically within a few weeks.