Gallbladder cancer (carcinoma of gallbladder) Overview:
Gallbladder cancer is one of common malignant tumors in biliary system. Occur in women outnumber men 2 to 4 times. Gallbladder cancer was particularly prevalent in the 50 to 70-year-old.
Causes of Gallbladder cancer (carcinoma of gallbladder):
The gallbladder cancer causes is unknown, clinical observation of benign gallbladder diseases and gallbladder often exist at the same time, the most common co-existence with gallstones. Most people think that chronic stimulation gallstone is an important pathogenic factors. Moosa noted that the "hidden stone" 5 ~ 20 years after the occurrence of gallbladder cancer were 3.3% ~ 50%. Domestic bulk Reports 20% ~ 82.6% of the gallbladder associated with gallstones, foreign reports as high as 54.3% ~ 100%. The occurrence of cancer and close to the size of stones, stone diameter of less than 10mm from the risk of cancer of 1.0, 20 ~ 22mm diameter stone the probability of 2.4, stone diameter, in the probability of more than 30mm can be as high as 10%. Was also suggested that the incidence of gallbladder cancer patients may be related to the lower end of the common bile duct and the convergence of the main pancreatic duct malformation of the junction there, as a result of this abnormal pancreatic juice into the bile duct, so that the concentration of bile in the pancreatic juice increased, causing chronic inflammation of the gallbladder, Health mucosal changes, and finally cancer.
Pathology of Gallbladder cancer (carcinoma of gallbladder):
Mostly occurred in the bottom of gallbladder, neck second, and less body. Histologically, adenocarcinoma 80%, undifferentiated carcinoma 6%, 3% squamous cell carcinoma, mixed carcinoma accounts for 1%. Gallbladder cancer infiltrating the surrounding organs can be directly or via lymphatic and blood circulation, nerves, means the transfer of bile duct and intra-abdominal cultivation. Terminally ill distant metastasis can occur, but generally occurred later and less.