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Esophageal cancer treatment

Early treatment of esophageal cancer is well. Even in late stages, if treated properly, can also be transformed for the better. Early on the more general should adopt the surgical treatment of lesions; of advanced lesions, and in the last paragraph of the patients, while radiation therapy is better.

1. Surgical treatment:
Surgery is the preferred method of treatment for esophageal cancer. Surgical resection of the lower rate of cancer in 90%, 50% in the middle of cancer, surgical resection of carcinoma of the upper rate of 56.3 percent on average ~ 92.9%.

Contraindication for surgery:

  • clinical x-ray examination confirmed esophageal disease, such as extensive and involved adjacent organs, such as the trachea, lung, mediastinum, aorta and so on.
  • serious heart and lung or liver and kidney dysfunction or cachexia can not tolerate surgery. In addition to the above, once diagnosed physical condition that should be taken to allow surgery. In addition, according to tolerate the disease can be divided into two types of surgery and radical surgery. Mainly to the late palliative surgery or radiotherapy can not cure the patients after, in order to address difficulties in the use of eating esophagogastric bypass, gastrostomy, esophageal cavity surgery, such as built-in pipe. Radical surgery and patients according to lesion specific circumstances. Should, in principle, a large part of esophageal resection, esophageal resection should be at least the scope of more than 5cm from the tumor.

    2. Radiation therapy:
    Radiotherapy of esophageal cancer, including radical and palliative. Cervical and upper thoracic esophageal cancer the trauma of surgery, and the high incidence of complications, and radiation injury in small, more effective than surgery, radiation therapy should be the first choice. General condition of patients who can, to enter into a smooth semi-liquid or liquid food, of thoracic esophageal carcinoma without supraclavicular lymph node metastasis and distant metastasis, no violations of the trachea, no signs of esophageal perforation and bleeding, lesion length <7 ~ 8cm and no medical contraindications, and can make radical radiotherapy. Other patients can be carried out to alleviate the esophageal obstruction and improve the eating difficulties, reduce pain, improve quality of life of patients and extended survival time of patients with palliative radiotherapy.

    3. Drug therapy:
    Medication: esophageal cancer cell proliferation cycle of about 7 days, than in normal esophageal epithelial cell cycle longer. The most commonly used drug BLM, MMC, adriamycin (ADM), 5 - fluorouracil, methotrexate, cyclohexyl nitrosourea Urea, C microphone hydrazone , Vindesine, etoposide, and DDP, a single drug chemotherapy in the 15% remission rate ~ 20% remission for 1 to 4 months. Most of the use of combination chemotherapy with DDP and BLM-based combined chemotherapy, the majority of more than 30% efficiency, in remission for about 6 months. Not only in combination chemotherapy for advanced esophageal cancer, is also used with surgery and radiation therapy combination therapy. Currently used clinically have combined chemotherapy DDP-BLM, BLM-ADM, DDP-VDS-BML and the DDP-ADM-5-Fu and so on. Clinical observation, DDP ,5-Fu and BLM chemotherapy with radiation, such as sensitizing effect, the past 10 years such as chemotherapy drugs and radiation sensitizers in treatment of esophageal cancer, and have achieved very good results.

    • Submitted by Health Studies on Tue, 04/14/2009 - 23:54
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