Disseminated intravascular coagulation Symptoms and Signs

Signs and symptoms of Acute Disseminated Intravascular Coagulation include:

  • Bleeding from at least 3 unrelated sites is typical and likely sites include
    Ears, mouth, nose and throat
    Gastrointestinal tract
    Respiratory tract
    Site of venepuncture or IV infusion
  • Confusion or disorientation
  • Fever
  • Extensive bruising
  • Hemorrhage
  • Adult respiratory distress syndrome (ARDS)
  • Skin may show various signs including:
    Petechiae
    Purpura
    Hemorrhagic bullae
    Acral cyanosis
    Skin necrosis of lower limbs (purpura fulminans)
    Signs of thrombosis
    Localised infarction and gangrene


  • Signs and symptoms of Chronic Disseminated Intravascular Coagulation include:

  • Deep vein or arterial thrombosis or embolism (clots)
  • Superficial venous thrombosis, especially without varicose veins
  • Multiple thrombotic sites at the same time
  • Serial thrombotic episodes