Colorectal Cancer Treatment

Treatment for colorectal cancer include surgical resection, combined with radiation therapy, chemotherapy, drug therapy and medical treatment, etc.; In addition to the use of early colorectal cancer treated by endoscopic resection and achieved good effect. Colon and colorectal cancer for the general term for cancer is one of common malignant tumors, the incidence of stomach cancer and esophageal cancer after.

1, surgical treatment: the only cure colorectal cancer is early cancer resection. Exploration have been found in cancer, but intestinal lesions when music can be free, in principle, that is, colorectal cancer should be removed in order to avoid future occurrence of intestinal obstruction; On the other hand, cancer often erosion, oozing, or with secondary infection case after excision of the whole body can be improved. There are a wide range of cancer metastasis, have unresectable lesions, it should be a shortcut, such as ostomy or palliative surgery.

2, Chemotherapy: Colorectal cancer after radical mastectomy, there are still about 50% of cases of recurrence and metastasis, mainly before the surgery failed to find occult metastases or patients failed to complete resection of lesions. Therefore, laparotomy before chemotherapy to the tumor or cancer mesocaval preoperative enema administration can prevent the cancer cell proliferation, destruction and elimination of cancer cells. Continue after chemotherapy, radical surgery has the potential to enhance the 5-year survival rate.

Chemotherapy for colorectal cancer to 5 - fluorouracil for the preferred drug. By intravenous injection in general, can give 12 ~ 15mg/kg, once a day, a total of five days, after the half-dose every other day until toxicity obvious symptoms such as vomiting, diarrhea, etc. that have developed to a total of 8 ~ 10g for a treatment. This response a little light for out-patient treatment. Have liver metastasis may be a day to 5 - fluorouracil 150 ~ 300mg, sub-oral, total of about 10 ~ 15g, intravenous drug efficacy than the poor. At present, more than that combined with chemotherapy, but not yet a mature program. It was suggested that MFC programs, namely: 5 - fluorouracil 500mg, mitomycin 4mg, cytarabine 50mg, joint application, the first 1 ~ 2 weeks, 2 times weekly intravenous injection, after 1 week, a total of 8 to 10 times as a course of treatment. Toxic symptoms of chemotherapy response in addition to the gastrointestinal tract, but also shows that bone marrow suppression, should be closely observed. In addition, there are commonly used chemotherapy drugs fluorouracil furan, excellent set-fu, cyclophosphamide, sodium nitrosourea B, cyclohexyl nitrosourea and such MeCCNU.

3, Radiation therapy: effect is still not satisfied, it was suggested that:

1) preoperative radiotherapy can reduce the tumor to improve the resection rate, reduce the regional lymph node metastasis, the spread of cancer cells during operation, and local recurrence;

2) postoperative radiotherapy: for operation radical cases, such as the tumor has penetrated the intestinal wall, violation of local lymph nodes, lymphatic and vascular, or surgical residual tumor after surgery, but there is no distant metastasis, and post-operative radiotherapy is advisable for;

3) radiotherapy alone: for advanced rectal cancer cases with low-dose radiation therapy, and sometimes can play a temporary stop bleeding, pain results.

4, Cryotherapy: Cryotherapy is the use of liquid nitrogen refrigerant, through the anus after the tumor has fully exposed the mirror, choose the size of shells ranging from the first contact-type frozen tumor tissue, to be effective in tumor destruction and damage. In the late surgery patients can not use as appropriate to reduce the suffering of patients, from the artificial anus, can be satisfied with the efficacy of chemotherapy.

5, Supportive therapy: including analgesia and supplementary nutrition.