Cardiac Carcinoma Causes

Like with other tumors, the causes of Cardiac Carcinoma is unknown, may be related to dietary factors, environmental factors, genetic factors and Helicobacter pylori infection. In addition the existence of such as chronic atrophic gastritis, gastric ulcer, gastric polyp, gastric epithelial cell metaplasia, gastric epithelial dysplasia and other precancerous changes.

Classification of Cardiac Carcinoma based on cause:

1. Advanced. Gastrointestinal Borrman typing typing is generally followed, the basic classification of the mushroom, ulcers, ulcers and infiltrating.

  • protruded type: the tumor was a clear edge to the cavity of the uplifted mass, showing cauliflower, nodular or polypoid mass, there are shallow ulcers;
  • localize ulcer type: the tumor is deep ulcers, the edge of organizations such as the dike-like uplift, with the normal tissue section clearly state;
  • infiltration ulcer type: the edge of the ulcer is not clear-cut boundaries and clear surrounding tissue;
  • infiltrating: intramural tumor infiltration in cardiac growth, uniform thickening of the Agency involved with the surrounding tissue without boundaries, shows radioactivity regular contraction of the surrounding mucosa.

    General classification is related with histological type, protruded and localize ulcer type is mainly well-differentiated adenocarcinoma and mucinous adenocarcinoma. Infiltration in the ulcer-type poorly differentiated adenocarcinoma and an increase in the proportion of mucinous adenocarcinoma. The majority of infiltrating poorly differentiated adenocarcinoma of diffuse type or mucinous adenocarcinoma. Prognosis of surgical treatment in order to uplift the best type, the limitations of type II ulcer, ulcer-type less invasive, infiltrating the worst.

    Cardia adenocarcinoma histologic types are mainly two categories: adenocarcinoma with a clear mucus secretion of mucinous adenocarcinoma. This second-class, according to their degree of differentiation into well-differentiated, poorly differentiated and diffuse type in three subtypes. The high and low degree of differentiation is closely related with the prognosis of surgery. In addition to adenocarcinoma and mucinous adenocarcinoma, there are some rare cardiac histological types, such as adenosquamous carcinoma, undifferentiated carcinoma, carcinoid (argyrophil cell carcinoma), as well as sarcoma and other cancers.

    2. Early. General form of the early cardiac and other parts of the stomach and the esophagus is similar to early cancer. Can be simply divided into three types:

  • depressed type: the Ministry of mucosal cancer showed mild irregular depression, there are a few shallow ulcers, with the surrounding normal mucosa is not clear boundaries, often under poor differentiation;
  • protruded type: canceration Department Rough mucosal thickening, a slight bulge, some of the performance for the plaque, nodule or polypoid, with the majority of well-differentiated adenocarcinoma;
  • insidious type: Department of mucosal lesions slightly deep color, slightly rough texture, in addition to the general no significant change in by histological examination before the diagnosis is 3 to compare the earliest forms.