Cancer of gastric remnant Causes

Cancer of gastric remnant is caused by gastric surgery. After subtotal gastrectomy or vagotomy, the stomach was low-acid or acid-free state of gastrin secretion to decline to reduce the protective mucus, gastric mucosal atrophy gradually. And post-operative stomach bile, pancreatic juice and intestinal fluid reflux of gastric mucosal damage, the formation of chronic atrophic gastritis, intestinal metaplasia and dysplasia, is important causes of Cancer of gastric remnant (gastric stump cancer).

After surgery to reduce stomach acid and is conducive to the growth of bacteria breeding in the stomach. Bacterial toxins and bacteria break down the bile metabolites, may have the role of promoter. Nitrate reductase containing bacteria can promote the synthesis of carcinogenic nitrosamines. These are carcinogenic, the role of promoter structures, the gastric mucosa may be cancerous.

Scars after gastric surgery, and even to stimulate the absorption of the suture may also be residue one of the factors of gastric cancer.

In short, the stomach of gastric surgery to change the normal anatomy and physiological functions, so that more exposure to gastric cancer, the role of promoter were under, when the lower immune function, cause Cancer of gastric remnant.