Bone Tumor Treatment
1. Treatment for benign bone tumor: To many local curettage and bone grafting, if can be completely removed, it will generally do not relapse, good on prognosis.
2. Treatment for malignant bone tumor:
Surgical resection is the primary means of treatment. Amputation, amputated joints is the most commonly used method. However, because of advances in chemotherapy, in recent years, some scholars begin segmentectomy for tumors (Enbolc resetion) or total femur resection with prosthetic replacement of artificial. It is said that the recent good results, but long-term effects are still very poor. The low degree of malignancy of the tumor, such as fibrosarcoma, limbs reservations "wide local resection and functional reconstruction" measures such as chemotherapy, is a preferable course of action. As for the corpse to joint replacement materials, some authors believe that "healing satisfied", but some cases of rejection of a larger, studies need to be overcome.
Chemical treatment of sub-systemic chemotherapy, local chemotherapy, the drugs commonly used doxorubicin and high-dose methotrexate, but the role of selective drugs do not have a strong, tumor cells in the division cycle is not synchronized, all affect the effectiveness of chemotherapy. Monoclonal antibodies used to carry drugs, selectively attack tumor cells (ie, "missile Ways"), is only a vision, there is the distance from the actual application.
Local chemotherapy, including intra-arterial infusion chemotherapy and continuing, with the effect of regional perfusion is better, the five-year survival rate is improved, but not totally "chemical cut-off" role. Future studies need to continue to improve the perfusion method, such as a reasonable combination, select the most appropriate infusion fluid temperature, reperfusion time for radical surgery and so on, should be explored in depth, make it better.
Immunotherapy: is still very much a non-specific immunotherapy in stage, the tumor antigen is a complex problem, there is no ideal specific immune therapy. Interferon is also expanding the scope of application, but its sources are limited, not widely used.
Radiotherapy treatment for bone tumors as an adjuvant therapy only.
