Bone Tumor Diagnosis
Bone Tumor is diagnosed by X-ray examination and Histology tests. X-ray examination of the specific site of bone tumors, the type, scope and decide the treatment approach can provide valuable information. Moreover, it needs to work closely with clinical manifestations and pathological examination in order to make an accurate diagnosis.
Benign bone tumor morphology rules, with the surrounding normal bone tissue clearly the limits to hardened edge for the industry, due to expansion and cortical thinning, but still intact, no periosteal reaction, malignant irregular images, edge blurring, melting phenomenon more pronounced bone, bone damage, thinning, breakage, missing, often primary malignant periosteal reaction, and its shape was the sun can be radial, onion skin-like and Codman triangle.
1. X-ray film for doctors to provide the course of the four tumor incidence information:
(A) the location of bone tumor: tumor can be located such as the epiphysis, the epiphysis can also do at end of long bones can be located, may also be located in a flat bone;
(B) bone tumor on the impact of the host: tumor and host bone boundary is to determine whether the invasive nature of the primary factors in disease, the border clearly demonstrate the growth of tumor infiltration of the weak and slow. In contrast, while the border shows that fuzzy strong tumor infiltration.
(C) of the host response to the tumor: host is always trying to eradicate the tumor, its package, the formation of fibrous tissue capsule, the rapid growth of the tumor infiltration and damage to bone envelope kind of reaction, but only at one end or the two tumor client to see the remnants of such a capsule, usually pass Codman triangle.
(D) the density of tumor tissue: bone density imaging if there is any change, can be suspected to have lesions of the organization, some for osteolytic tumor lesions, such as giant cell tumor of bone, and some for osteoblastic lesions, as Snowflake bone or irregular shape, such as osteosarcoma, chondrosarcoma.
Happened in the pelvis, spine and other parts of the tumor, general X-ray Can not very well displayed, CT scan, B-ultrasonic, MRI, ECT that is new imaging technology can help identify the location and extent of tumor.
Bone scan in ordinary X-ray can have positive changes have not yet shown that the original hair, the existence of secondary bone tumor.
2. Histology examination
Diagnosis of bone tumor finally achieve depends on histology examination, usually always obtain a tissue biopsy. Biopsy has required the implementation of experienced doctors, it is necessary to have diagnostic significance of the guarantee of the organization. Incision should be designed to take care of the follow-up surgery, at least to reduce the proliferation of tumor cells and normal tissues adjacent to the pollution, must not think for minor surgery and biopsy from the rash, the material should be to avoid necrotic areas, some check many sites. Cancer of the external part of many for the reaction zone, and sometimes not enough to make a firm diagnosis, however, pathological examination has its limitations, such as fatigue fractures, myositis ossificans easily misdiagnosed as osteosarcoma; hyperparathyroidism brown tumor at the time of easy misdiagnosed as giant cell tumor; cartilage sources difficult to distinguish between benign and malignant tumor, etc..
Diagnosis of certain bone tumors, the laboratory must have the assistance check, such as in patients with osteosarcoma alkaline phosphatase may be increased in patients with multiple myeloma may have pots of blood, urine protein, this week's positive, there is calcium in patients with brown tumor , phosphorus and other abnormalities.