Behcet Syndrome Treatment
Principle of Behcet Syndrome (Behcet's Disease) treatment is to alleviate symptoms and reduce organ damage. Patient with non involvement of vital organs, treatment is first choice colchicine drugs, for visceral involvement particularly the impact of eye disease to be more associated medication.
1. Colchicine: This drug has the role of anti-chemokine, is used to prevent ulcers, iris inflammation, synovitis and phlebitis. Per 0.5mg, daily 2 to 3 times. There are bone marrow toxicity by the suppression, nausea, vomiting, loss of appetite, diarrhea and constipation and so on.
2. Adrenocorticotropic hormone: the general use of prednisone 30 ~ 40mg, day 1, oral, intravenous drip can be severe hydrocortisone or dexamethasone. To be replaced after the oral symptoms. Although corticosteroids can oral ulcers and arthritis symptoms, but to reduce or tend to relapse after stopping the disease. On the central nervous system damage and more difficult to cure.
3. Immunosuppressive drugs: immunosuppressive agents for severe uveitis pigment 50mg, 3 times a day or 200mg, intravenous injection, 1 day or the next day. Should pay attention to the use of leukopenia, gastrointestinal adverse reactions and side effects such as hair loss. In recent years, the trial of cyclosporin A (CycosyrinA) with a certain effect on the eye. Damage to other systems on the apparent lack of efficacy. Every time 125 ~ 300mg, work 1 day, 3-month course of treatment was 1. Tripterygium glycosides, each 30mg, 3 times a day. There are leukopenia, thrombocytopenia, loss of appetite, amenorrhea, reduction in side effects such as sperm. Kening tumor can also be used, methotrexate and other immunosuppressive agents.
4. Other treatment: patient with tuberculosis were given anti-TB drugs.
