Barrett's esophagus Diagnosis

Barrett's esophagus diagnosis should be based on patient history, clinical symptoms, esophageal manometry, pH monitoring, endoscopy and biopsy, in which most of the diagnostic value of endoscopy and biopsy methods.

Laboratory tests: detection of esophageal motility in patients with BE lower esophageal sphincter dysfunction, reduced lower esophageal pressure and easy form of gastroesophageal reflux, and for acid reflux to remove the ability to drop in on the patients with esophageal pressure and pH monitoring , BE prompted the existence of a certain reference value. Is generally believed that the pressure below the lower esophageal sphincter dysfunction 1.33kPa for. Ranson measured by normal people, such as lower esophageal sphincter pressure of 2.6kPa ± 7kPa, and in patients with BE for extensive 0.97kPa ± 3.46kPa, was significantly lower than the control group. When endoscopy can not determine when the lower esophageal borders, but also in the pressure under the guidance of biopsy.

Other test is performed for diagnosis of Barrett's esophagus include:

1.X-ray test. More difficult to find Barrett esophagus, a hiatal hernia and reflux esophagitis performance, rather than the specific disease. Found to have peptic esophageal stricture or ulceration body should be suspected Barrett esophagus.

2. Esophageal endoscopy. Barrett esophagus to in patients with gastroesophageal junction at the top appears granular, columnar epithelium of the red zone, and reflux esophagitis there signs of injury. Biopsy can confirm that and find the columnar metaplasia.

3. Esophageal manometry and pH monitoring. Barrett's esophagus patients with acid reflux, alkaline reflux material can be seen a long time contact with the pressure performance of gastroesophageal reflux, the lower esophageal sphincter pressure of more general lower reflux patients.