Amebic liver abscess Treatment

Treatment for amebic liver abscess include medication, Anti-amoebic therapy, Liver puncture drainage, Antibiotic therapy and Surgical treatment.

Medication:
1. Anti-amoebic therapy: selection of amebic drugs to kill the organization, supplemented by intestinal amebic drugs to kill in order to cure. Metronidazole is currently most preferred dose 1.2g / day, 10 ~ 30 days of treatment, cure rate of 90%. No complications within 72 hours after medication liver pain, fever and other clinical conditions significantly improved, body temperature in the 6 to 9 days faded, hepatomegaly, tenderness, leukocytosis, such as in the treatment of about two weeks after recovery, until the absorption Vomica 4 months or so. Second-generation drugs nitroimidazoles dynamic resistance, pharmacokinetics characteristics and metronidazole, but much longer half-life more effective than amebic abscess enteropathy. Efficacy of a small number of poor single-Glass triazole can be used for or in accordance with chloroquine Mitin, it should be noted that the former have a high relapse rate, the latter have more cardiovascular and gastrointestinal reactions. The treatment of post-treatment with a conventional enteral plus anti-amebic drugs, to eradicate the possibility of compound.

2. Liver puncture drainage: the early selection of effective drug treatment, a number of liver abscess puncture is no longer necessary. Appropriate drug therapy for 5 to 7 days, no significant improvement of clinical conditions, or significant liver local uplift, marked tenderness, and the risk of perforation from the use of drainage. Puncture the best in the anti-amoebic drug therapy for 2 to 4 days. Puncture site of the election right anterior axillary line of multi-section 8 or section 9 of intercostal, internal organs or right in the ninth or tenth intercostal online or liver swell, the most obvious tenderness, the best in ultrasonic positioning under exploration. The number depending on the need to puncture the quiet condition, each should try to puncture the net pumping pus, pus in the volume of 200ml often need more than 3 to 5 days after repeated aspiration. Vomica large pumping were to speed up the recovery. In recent years, interventional therapy, guided by the guide needle drainage for sustained closure can be repeatedly removed from the puncture, the shortcomings of secondary infection, the use of qualified persons.

3. Antibiotic therapy: A mixed infection, depending on the type of bacteria to the choice of appropriate systemic antibiotics.

Surgical treatment:

Liver abscess required surgical drainage are generally <5%. Its indications are as follows:

1. Anti-amoebic drug treatment and drainage losers;
2. abscess special location, close to hilar and large blood vessels or location too deep (> 8cm), puncture injuries to neighboring organs were easy;
3. abscess perforation into the abdominal cavity or the adjacent organs from the poor drainage;
4. abscess are secondary bacterial infection, drug treatment beyond the control of persons;
5. multiple abscesses, so that drainage problems or failures;
6. easy left lobe liver abscess perforation to the pericardium, abdominal puncture prone pollution should also be considered for surgery.

Liver abscess is not the same standard of cure, the symptoms and signs generally disappear as the clinical cure, liver abscess most of the filling defect in the 6 months to be fully absorbed, and 10% sustainable directors to one year. A small number of larger lesions may be residual liver cyst. ESR can also be used as a reference indicator.