Acute Leukemia Symptoms and Signs

1. Common symptoms of Acute Leukemia include: fever, progressive anemia, marked bleeding tendency or bone and joint pain. From the slow onset of old age and some young people most sick, his condition gradually progress. Many such patients can not afford to carry out related fatigue, pale pale and tired after the flustered shortness of breath, lack of appetite, weight loss or fever of unknown origin such as the first symptom. In addition, a small number of patients can be convulsions, blindness, toothache, gingival swelling, pericardial effusion, such as paraplegia of both lower extremities as the first symptom onset.

2. Fever and infection: A. fever are the most common symptoms of leukemia, one can no longer happen at different stages of the disease and have varying degrees of heat and hot type. Fever is mainly due to infections, to one of angina, oral inflammation, the most common perianal inflammation, pneumonia, tonsillitis, gingivitis, perianal abscess were also more common. ear inflammation, enteritis, appendicitis, pyelonephritis, also can be seen that severe cases, infection can also happen septicemia , such as sepsis. B. infections to bacterial pathogens found in the incidence of early to mainly gram-positive cocci. virus infection, although less common but often more dangerous, cytomegalovirus, measles or chickenpox virus infection complicated by easy pneumonia, have to pay attention to.

3. Hemorrhage: hemorrhage also are common symptoms of leukemia, bleeding all over the body parts can be to the skin, gums, nasal bleeding the most common, but also there is the retina, ear, and intracranial hemorrhage, gastrointestinal, respiratory and other internal organs bleeding. Female menorrhagia and but also the more common first symptom. AML of the M3 and M5 subtypes of bleeding is more serious, especially in patients prone M3 concurrent disseminated intravascular coagulation (DIC) and died of intracranial hemorrhage.

4. Anemia: Early to occur, a small number of cases can be diagnosed before a few months or years to appear refractory anemia future develop into leukemia. Patients are often accompanied by fatigue, pale face, palpitations, shortness of breath, symptoms such as lower extremity edema . anemia can be found in various types of leukemia, but more see elderly AML patients, many patients often as the first symptom of anemia.

5. Leukemic cell infiltration signs

  • liver, splenomegaly, swollen lymph nodes
  • nervous system: The main lesion was bleeding and leukemia infiltration
  • bone and joint: bone and joint pain are the important one of the symptoms of leukemia, ALL found.
  • skin; may have specific and non-specific two kinds of skin damage, which manifested as rash, impetigo, lumps, nodules, erythroderma, exfoliative dermatitis and so on, was particularly prevalent in the adult monocytic leukemia, the latter while the performance of many skin ecchymosis, and other spots.