Acute and Chronic Amebic dysentery

Acute Amebic dysentery (Intestinal amoebiasis): the destruction of intestinal mucosa cells, resulting in erosion and superficial ulceration. If the disease continues to progress, lesions become darker involved submucosa, while the formation of a typical big mouth and small at the end of the flask-like ulcers, its basement for the mucosal layer, cavity filled with brown necrotic material, containing the cell lysis debris, mucus and Zi agent body, when the contents generated from clinical samples have dysentery. Ulceration of the mucous membrane between the most complete, and the lesions of bacillary dysentery different. Entamoeba submucosa to continue to progress, due to a more loose organization, the intestinal parasite cis on both sides of the expansion of the axial length, a large number of organizations formed by dissolving the same number of fistula of the honeycomb region. A lot of inflammatory response around the lesions is generally limited to a few lymphocytes and plasma cell infiltration, if there is secondary bacterial infection may be a large number of neutrophil infiltration. Capillary lesion prone to thrombosis, bleeding, blood spots, as well as necrosis, due to the destruction of small blood vessels, so effluents containing more red blood cells. Serious cases of disease can be as deep as, or even perforation serosal layer, but the development of the Department of progressive disease, and serosal layer easily with neighboring tissue adhesion, it is also the opportunity to acute intestinal little wear. Amebic ulcer as a result of the general deeply corrosive blood vessels, can cause a large number of intestinal bleeding, the healing process in the disease subsided in the tissue reaction, the disappearance of lymphocytes and substituting connective tissue.

Chronic Amebic dysentery (Intestinal amoebiasis): This period is characterized by intestinal epithelial hyperplasia, appear granulation tissue in the bottom of ulcers, ulcer surrounded by fibrous tissue hyperplasia. Organization to undermine the existence of regular and healing to the intestinal wall thickening, stenosis mesocaval. Connective tissue showed tumor-like proliferation of dual and become amoeba tumor, was particularly prevalent in the anus, anal straight off the junction, transverse colon and cecum. Amebic tumor sometimes great, quality hardware, it is difficult to identify with colorectal cancer phase.

Amebic trophozoites can enter the portal vein blood flow in intrahepatic abscess formation, and can form emboli flowing into lungs, brain, spleen and other tissues and organs, the form of abscess.